Cell-Free Biomanufacturing
A type of manufacturing that utilizes synthetic biological and biochemical systems to produce commercially important molecules and chemicals to make the products our lives depend upon every day.
The world is using unsustainable and inefficient manufacturing processes to make the fuels, foods, medicines and products to satisfy the world’s growing population. Working to solve this critical and complex global problem has led to the innovation and industry known as biomanufacturing.
Scientists, university labs and biotech entrepreneurs have created companies around the world focused on ways to create products from synthetic biology methods and biomanufacturing. But it was hard to use for mass production until Invizyne invented Cell-Free Biomanufacturing.
TECHNOLOGY
Nature provides us with countless chemicals that can improve our lives. Trees and plants often supply them, but in such small amounts that they’re hard to extract, leading to waste and environmental degradation. To harness natural chemicals more effectively, synthetic biology first attempted to rewire living cells to make them easier to extract. But cells are complicated and not easily rewired.
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Invizyne’s new approach, SimplePath streamlines synthetic biology by removing cells altogether, along with their complexities. Using our proprietary, sustainable enzyme systems we can build simple, efficient reactors for chemical production. The Invizyne approach allows for:
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Fast design-build-test-learn cycles for rapid optimization
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Reliable scaling of production
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Simplified product purification
Unleashing enzymes for production outside the cell allows us to achieve the safety, sustainability and diversity found in nature, along with the scale found in traditional chemical manufacturing.
SCIENTIFIC VALIDATION
Invizyne's scientific approach using cell-free biomanufacturing has been published multiple times in peer-reviewed high-impact journals.
PATENTED TECHNOLOGY
In addition to multiple patents currently pending, Invizyne's scientific foundation is already resting on multiple issued patents, including the ones listed below.
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Synthetic biochemistry molecular purge valve module that maintain co-factor balance
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Cell-free metabolic pathway for glucose metabolism with a molecular purge valve
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Biosynthetic platform for the production of cannabinoids and other prenylated compounds
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Biosynthesis of cyclolavandulyl derivatives of aromatic compounds
MARKETS & PRODUCTS
Invizyne's pioneering platform has been applied to produce a wide variety of high value and difficult to make target molecules, with exceptional success in cannabinoids, biofuels and terpenes, where we’ve achieved orders of magnitude higher concentrations than what is possible using yeast-based methods.
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Contact us to learn more on how we can provide solutions for:
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Natural Ingredients: cannabinoids, flavor enhancers for food and beverage products, fragrances, nutraceuticals, organic compounds​
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Pharmaceuticals: natural products with therapeutic properties
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Chemicals: commodity chemicals, specialty chemicals, biofuels
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LEADERSHIP
Our team combines decades of experience in biochemistry, biophysics, molecular biology, engineering, with sound and innovative business practices and principles.
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MICHAEL HELTZEN
CEO
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TYLER KORMAN, PhD
Co-founder & Board
VP of Research
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PAUL OPGENORTH, PhD
Co-founder & Board
VP of Development
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Board of Directors
MO HAYAT
Chairman & Co-founder
ANTHONY DiGIANDOMENICO
Board Member​
CHRISTOPHER MARLETT
Board Member​
Scientific Advisory Board
JAMES BOWIE, PhD
Co-founder & Board
Professor Dept of Chemistry and Biochemistry at UCLA
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YI TANG, PhD
Chancellor Professor at UCLA
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JIM LALONDE, PhD
Formerly SVP of R&D at Codexis
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